Severe Sepsis

 Severe Sepsis and Septic Shock

R65.2 Severe sepsis

R65.20 …… without septic shock

R65.21 …… with septic shock

 

 Remember the Severe Sepsis definition (Established Sepsis + Hypo-perfusion)

Sepsis-induced hypotension

Lactate above upper limits laboratory normal

Urine output < 0.5 mL/kg/hr for more than 2 hrs despite adequate fluid resuscitation

Acute lung injury with PaO2/FiO2 <250 in the absence of pneumonia as infection source

Acute lung injury with PaO2/FiO2 < 200 in the presence of pneumonia as infection source

Creatinine > 2.0 mg/dL (176.8 μmol/L)

Bilirubin > 2 mg/dL (34.2μmol/L)

Platelet count < 100,000 μL

Coagulopathy (international normalized ratio > 1.5)